NAPLEX Practice Exam 2026 – Comprehensive Test Preparation

Vericiguat is an sGC activator commonly used to treat heart failure by increasing the levels of cyclic guanosine monophosphate (cGMP), a signaling molecule that helps relax the heart and blood vessels.

Sacubitril/Valsartan (A) is a combination medication used to reduce the risk of death in patients with heart failure. It works by reducing the levels of certain hormones that cause the heart to work harder. It is not an sGC activator.

Dapagliflozin (C) is a medication used to treat type 2 diabetes that has been shown to have some benefits in reducing the risk of heart failure hospitalization. However, it is not an sGC activator and is not primarily used for heart failure.

Spironolactone (D) is a diuretic commonly used to treat high blood pressure and heart failure. It works by blocking the activity of certain hormones that can contribute to heart failure. It is not an sGC activator and is typically not used as a first-line treatment for heart failure.