NAPLEX Practice Exam 2026 – Comprehensive Test Preparation

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Which antibiotic is recommended for the treatment of syphilis?

Piperacillin/tazobactam

Dicloxacillin

Penicillin G Benzathine

Penicillin G Benzathine is the recommended antibiotic for the treatment of syphilis. It is the first-line treatment for this infection according to the Centers for Disease Control and Prevention (CDC) guidelines. Piperacillin/tazobactam, Dicloxacillin, and Ceftriaxone are not the preferred treatments for syphilis. Therefore, Penicillin G Benzathine is the correct choice as it has shown high efficacy in treating syphilis infections.

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Ceftriaxone

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