NAPLEX Practice Exam 2025 – Comprehensive Test Preparation

Question: 1 / 1820

Which generation of cephalosporins includes drugs with broad gram-negative activity including HNPEK, CAPES, and Pseudomonas?

1st generation

2nd generation

3rd generation

4th generation

The fourth generation of cephalosporins is considered to have the broadest spectrum of activity against gram-negative bacteria, including organisms such as HNPEK, CAPES, and Pseudomonas. The first generation is primarily effective against gram-positive bacteria, while the second and third generations have increasing levels of gram-negative activity, but not to the extent of the fourth generation. Therefore, options A, B, and C are incorrect.

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