NAPLEX Practice Exam 2025 – Comprehensive Test Preparation

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Question: 1 / 1820

Which is a CYP inhibitor?

Smoking

Grapefruit

Grapefruit is a CYP inhibitor because it contains compounds that can inhibit the activity of specific cytochrome P450 enzymes in the liver. This inhibition can result in altered metabolism of certain drugs that are substrates for these enzymes, leading to potential drug interactions and changes in drug levels in the body.

Smoking, phenytoin, and carbamazepine are not CYP inhibitors. Smoking can induce the activity of some CYP enzymes, leading to increased metabolism of certain drugs. Phenytoin and carbamazepine are known to induce the activity of CYP enzymes rather than inhibit them, impacting the metabolism of various drugs in the body.

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Phenytoin

Carbamazepine

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