NAPLEX Practice Exam 2026 – Comprehensive Test Preparation

Question: 1 / 1820

Which medication has a boxed warning for QT prolongation?

Asenapine

Paliperidone

Ziprasidone

Ziprasidone (Choice C) is the only medication mentioned that has a boxed warning specifically for QT prolongation. Asenapine (Choice A) has a boxed warning for increased mortality in elderly patients with dementia-related psychosis and second-generation antipsychotic drugs (SGA). Paliperidone (Choice B) has a boxed warning for increased risk of death in elderly patients with dementia-related psychosis and also for cerebrovascular events in elderly patients with dementia-related psychosis. Risperidone (Choice D) has a boxed warning for increased risk of death in elderly patients with dementia-related psychosis and also for increased risk of stroke and transient ischemic attacks in elderly patients with dementia-related psychosis.

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Risperidone

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